Daidzein-d4

Daidzein-d4 is the deuterium labeled Daidzein. Daidzein is a soy isoflavone, which acts as a PPAR activator.

Product Specifications

CAS Number

[1219803-57-2]

UNSPSC

12352005

Hazard Statement

H315, H319

Target

Endogenous Metabolite; PPAR

Type

Isotope-Labeled Compounds

Related Pathways

Cell Cycle/DNA Damage; Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor

Field of Research

Endocrinology; Cancer

Purity

98.93

Solubility

10 mM in DMSO|DMF : ≥ 10mg/mL|DMSO : ≥ 30mg/mL|Ethanol : ≥ 0.1mg/mL

Smiles

O=C1C2=CC=C(O)C=C2OC=C1C3=C([2H])C([2H])=C(C([2H])=C3[2H])O

Molecular Formula

C15H6D4O4

Molecular Weight

258.26

Precautions

H315, H319

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216. |[2]Kim E, et al. Daidzein Augments Cholesterol Homeostasis via ApoE to Promote Functional Recovery in Chronic Stroke. J Neurosci. 2015 Nov 11;35 (45) :15113-26.|[3]Sakamoto Y1, et al. The Dietary Isoflavone Daidzein Reduces Expression of Pro-Inflammatory Genes through PPARα/γ and JNK Pathways in Adipocyte and Macrophage Co-Cultures. PLoS One. 2016 Feb 22;11 (2) :e0149676.