Vorinostat (GMP)

Vorinostat (GMP) is a GMP grade Vorinosta (HY-10221) . GMP-grade small molecules can be used as auxiliary agents in cell therapy. Vorinostat is a potent, orally available HDAC1, HDAC2, HDAC3 (Class I), HDAC6 and Inhibitors of HDAC7 (Class II) and Class IV (HDAC11) [1].

Product Specifications

CAS Number

[149647-78-9]

Product Name Alternative

SAHA (GMP) ; Suberoylanilide hydroxamic acid (GMP)

UNSPSC

12352005

Hazard Statement

H341-H360

Target

HDAC

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage; Epigenetics

Field of Research

Cancer; Infection

Assay Protocol

https://www.medchemexpress.com/vorinostat-gmp.html

Solubility

10 mM in DMSO

Smiles

O=C(NC1=CC=CC=C1)CCCCCCC(NO)=O

Molecular Formula

C14H20N2O3

Molecular Weight

264.32

Precautions

P280-P405-P501

References & Citations

[1]Hrzenjak A, et al. Histone deacetylase inhibitor vorinostat suppresses the growth of uterine sarcomas in vitro and in vivo. Mol Cancer. 2010 Mar 4;9:49.