BMS-509744
Product Specifications
UNSPSC Description
BMS-509744 is a potent, selective and ATP competitive Itk inhibitor with an IC50 of 19 nM.
Target Antigen
Itk
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/BMS-509744.html
Purity
98.09
Solubility
DMSO : 21.9 mg/mL (ultrasonic;warming)
Smiles
CC(C(C)(C)C)NCC1=CC=C(C(NC2=NC=C(SC3=CC(C(N4CCN(C(C)=O)CC4)=O)=C(OC)C=C3C)S2)=O)C=C1
Molecular Weight
623.83
References & Citations
[1]Lin TA, et al. Selective Itk inhibitors block T-cell activation and murine lung inflammation. Biochemistry.?2004 Aug 31;43(34):11056-62.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-11092/BMS-509744-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-11092/BMS-509744-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
439575-02-7
Available Sizes
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