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BMS-509744

BMS-509744 is a potent, selective and ATP competitive Itk inhibitor with an IC50 of 19 nM.

Product Specifications

CAS Number

439575-02-7

UNSPSC

12352005

Target

Itk

Type

Reference compound

Related Pathways

Protein Tyrosine Kinase/RTK

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/BMS-509744.html

Concentration

10mM

Purity

98.09

Solubility

DMSO : 66.67 mg/mL (ultrasonic)

Smiles

CC(C(C)(C)C)NCC1=CC=C(C(NC2=NC=C(SC3=CC(C(N4CCN(C(C)=O)CC4)=O)=C(OC)C=C3C)S2)=O)C=C1

Molecular Formula

C32H41N5O4S2

Molecular Weight

623.83

References & Citations

[1]Lin TA, et al. Selective Itk inhibitors block T-cell activation and murine lung inflammation. Biochemistry.?2004 Aug 31;43 (34) :11056-62.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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