Anti-Mouse osteopontin/SPP1 Antibody (103D6)

Anti-Mouse osteopontin/SPP1 Antibody (103D6) is a mouse-derived anti-mouse osteopontin/SPP1 IgG2c κ type antibody inhibitor. Anti-Mouse osteopontin/SPP1 Antibody (103D6) increases cytotoxic T lymphocyte lytic activity and suppresses colon tumor growth. Anti-Mouse osteopontin/SPP1 Antibody (103D6) ameliorates liver injury in common bile duct ligation (CBDL) -induced primary sclerosing cholangitis mice models[1][2].

Product Specifications

CAS Number

[9007-83-4]

UNSPSC

12352203

Hazard Statement

H302, H315, H319, H335

Target

Osteopontin

Type

Inhibitory Antibodies

Related Pathways

Immunology/Inflammation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/anti-mouse-osteopontin-spp1-antibody-103d6.html

Purity

95.00

Solubility

10 mM in DMSO

Smiles

[Anti-Mouseosteopontin/SPP1Antibody(103D6)]

Molecular Weight

(150 kDa)

Precautions

H302, H315, H319, H335

References & Citations

[1]Klement JD, et al. Osteopontin Blockade Immunotherapy Increases Cytotoxic T Lymphocyte Lytic Activity and Suppresses Colon Tumor Progression. Cancers (Basel) . 2021 Feb 28;13 (5) :1006.|[2]De Muynck K, et al. Osteopontin characterizes bile duct-associated macrophages and correlates with liver fibrosis severity in primary sclerosing cholangitis. Hepatology. 2024 Feb 1;79 (2) :269-288.