TLR7 agonist 26

TLR7 agonist 26 (Compound 4) is a potent Toll-like receptor 7 (TLR7) agonist, with an EC50 of 225.5 nM. TLR7 agonist 26 shows immunopotentiating effects[1].

Product Specifications

CAS Number

[1641544-09-3]

UNSPSC

12352005

Target

Toll-like Receptor (TLR)

Type

Reference compound

Related Pathways

Immunology/Inflammation

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/tlr7-agonist-26.html

Smiles

OC1=NC2=C(N)N=C(OCCCC)N=C2N1CC3=CC=C(C(O)=O)C=C3

Molecular Formula

C17H19N5O4

Molecular Weight

357.36

References & Citations

[1]Janež Š, et al. Linker Chemistry and Connectivity Fine-Tune the Immune Response and Kinetic Solubility of Conjugated NOD2/TLR7 Agonists. Bioconjug Chem. 2024 Oct 10.