TLR7 agonist 26
TLR7 agonist 26 (Compound 4) is a potent Toll-like receptor 7 (TLR7) agonist, with an EC50 of 225.5 nM. TLR7 agonist 26 shows immunopotentiating effects[1].
Product Specifications
CAS Number
[1641544-09-3]
UNSPSC
12352005
Target
Toll-like Receptor (TLR)
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/tlr7-agonist-26.html
Smiles
OC1=NC2=C(N)N=C(OCCCC)N=C2N1CC3=CC=C(C(O)=O)C=C3
Molecular Formula
C17H19N5O4
Molecular Weight
357.36
References & Citations
[1]Janež Š, et al. Linker Chemistry and Connectivity Fine-Tune the Immune Response and Kinetic Solubility of Conjugated NOD2/TLR7 Agonists. Bioconjug Chem. 2024 Oct 10.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
TLR7
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