ODN TTAGGG
ODN TTAGGG (A151), inhibitory oligonucleotide (ODN), is a TLR9, AIM2 and cGAS antagonist. ODN TTAGGG is immunosuppressive and inhibits AIM2 inflammasome activation, as well as cGAS activation, by competing with DNA. ODN TTAGGG can be used in the study of lupus erythematosus and other related autoimmune diseases. ODN TTAGGG sequence: 5'-T-T-A-G-G-G-T-T-A-G-G-G-T-T-A-G-G-G-T-T-A-G-G-G-3'[1][2].
Product Specifications
CAS Number
1801724-76-4
Product Name Alternative
ODN A151
UNSPSC
12352208
Target
AIM2; Toll-like Receptor (TLR)
Type
Oligonucleotides
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/odn-ttaggg.html
Purity
99.87
Solubility
H2O : ≥ 20 mg/mL
Smiles
[DNA,d(P-thio)(T-T-A-G-G-G-T-T-A-G-G-G-T-T-A-G-G-G-T-T-A-G-G-G)]
Molecular Weight
7944.30
References & Citations
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
Scientific Category
Oligonucleotides
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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