IRAK4 ligand-12
Product Specifications
UNSPSC Description
IRAK4 ligand-12 is a PROTAC target protein ligand (Ligands for Target Protein for PROTACs). IRAK4 ligand-12 can be used for the synthesis of KTX-951 (HY-148290)[1].
Target Antigen
Ligands for Target Protein for PROTAC
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/irak4-ligand-12.html
Smiles
O=C(C1=CC=CC(C(F)(F)C)=N1)NC2=CC3=CN([C@@H]4CC[C@H](CC4)C=O)N=C3C=C2OC
Molecular Weight
442.46
References & Citations
[1]Walker D H, et al. Degraders targeting both IRAK4 and IMiD substrates show combinatorial effects leading to broader activity with durable and complete regressions in MYD88 mutant lymphoma xenografts in vivo. Cancer Research, 2020, 80(16_Supplement): 5222-5222.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-48932/IRAK4-ligand-12-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-48932/
Clinical Information
No Development Reported
CAS Number
2573304-97-7
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