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4-Aminohippuric acid

4-Aminohippuric acid (p-Aminohippuric acid) is a coordination ligand for metal ions (such as Cu2+, Fe3+, Hg2+) and a functionalization reagent for nanomaterials. 4-Aminohippuric acid can coordinate with metal ions or modify the surface of materials such as carbon nanotubes and gold nanoparticles through amino and carboxyl groups. 4-Aminohippuric acid can form stable complexes with metal ions or participate in the synthesis of nanomaterials as a reducing agent/stabilizer, enriching metal ions or giving nanoparticles peroxidase-mimicking activity. 4-Aminohippuric acid can be used to construct highly sensitive electrochemical sensors or colorimetric sensors to detect and quantitatively analyze heavy metal ions such as copper, iron, and mercury in environmental water samples and biological samples. 4-Aminohippuric acid may also be a biomarker for attention-deficit/hyperactivity disorder (ADHD) [1][2][3].

Product Specifications

CAS Number

[61-78-9]

Product Name Alternative

P-Aminohippuric acid

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Others

Type

Natural Products

Related Pathways

Others

Field of Research

Metabolic Disease; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/4-Aminohippuric-acid.html

Concentration

10mM

Purity

99.84

Solubility

DMSO : 50 mg/mL (ultrasonic) |H2O : ≥ 1.7 mg/mL

Smiles

O=C(O)CNC(C1=CC=C(N)C=C1)=O

Molecular Formula

C9H10N2O3

Molecular Weight

194.19

Precautions

H302, H315, H319, H335

References & Citations

[1]Rastogi L, et al. Intrinsic peroxidase-like activity of 4-amino hippuric acid reduced/stabilized gold nanoparticles and its application in the selective determination of mercury and iron in ground water. Spectrochim Acta A Mol Biomol Spectrosc. 2020 Mar 5;228:117805.|[2]Mohadesi A, et al. 4-Aminohippuric acid-functionalized carbon nanotubes for stripping voltammetric determination of copper (II) ions[J]. Electrochemistry, 2016, 84 (3) : 138-142.|[3]Wang LJ, et al. Novel plasma metabolite markers of attention-deficit/hyperactivity disorder identified using high-performance chemical isotope labelling-based liquid chromatography-mass spectrometry. World J Biol Psychiatry. 2021 Feb;22 (2) :139-148.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Natural Products

Clinical Information

Launched

Available Sizes

Curated Selection

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