DL-AP4 (sodium)
DL-AP4 sodium (2-Amino-4-phosphonobutyric acid sodium) is an agonist for metabotropic glutamate receptors (mGluR). DL-AP4 sodium binds to mGluR4, activates the signaling pathway that is negatively correlated with adenylate cyclase, and inhibits the Forskolin -induced production of cAMP. DL-AP4 sodium is also an inhibitor for ON channel, that reduces the sensitivity of photoreceptors to brightness changes[1][2].
Product Specifications
CAS Number
1263093-79-3
Product Name Alternative
2-Amino-4-phosphonobutyric acid (sodium)
UNSPSC
12352211
Target
MGluR
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease; Others
Assay Protocol
https://www.medchemexpress.com/dl-ap4-sodium.html
Smiles
OC(C(N)CCP(O)(O[Na])=O)=O
Molecular Formula
C4H9NNaO5P
Molecular Weight
205.08
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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