Human CCNB1 Protein

<strong>Human CCNB1 Protein</strong>_x000D_ <strong>Catalog number:</strong> B2011853_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 20 µg_x000D_ <strong>Molecular Weight or Concentration:</strong> 250 µg/mL_x000D_ <strong>Supplied as:</strong> Solution_x000D_ <strong>Applications:</strong> molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> -20 °C_x000D_ <strong>Keywords:</strong> CCNB 1, CCNB-1, CCNB 1 protein, CCNB1, Cyclin B1 protein, CCNB protein, CCNB-1 protein_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Xia P, Zhang H, Xu K, Jiang X, Gao M, Wang G, Liu Y, Yao Y, Chen X, Ma W, Zhang Z, Yuan Y. MYC-targeted WDR4 promotes proliferation, metastasis, and sorafenib resistance by inducing CCNB1 translation in hepatocellular carcinoma Cell Death Dis. 2021 Jul 9;12(7):691._x000D_ 2: Zou Y, Ruan S, Jin L, Chen Z, Han H, Zhang Y, Jian Z, Lin Y, Shi N, Jin H. CDK1, CCNB1, and CCNB2 are Prognostic Biomarkers and Correlated with Immune Infiltration in Hepatocellular Carcinoma Med Sci Monit. 2020 Aug 31;26:e925289._x000D_ 3: Zhang H, Zhang X, Li X, Meng WB, Bai ZT, Rui SZ, Wang ZF, Zhou WC, Jin XD. Effect of CCNB1 silencing on cell cycle, senescence, and apoptosis through the p53 signaling pathway in pancreatic cancer J Cell Physiol. 2018 Jan;234(1):619-631._x000D_ 4: Chai N, Xie HH, Yin JP, Sa KD, Guo Y, Wang M, Liu J, Zhang XF, Zhang X, Yin H, Nie YZ, Wu KC, Yang AG, Zhang R. FOXM1 promotes proliferation in human hepatocellular carcinoma cells by transcriptional activation of CCNB1 Biochem Biophys Res Commun. 2018 Jun 12;500(4):924-929._x000D_ 5: Xing Z, Wang X, Liu J, Zhang M, Feng K, Wang X. Expression and prognostic value of CDK1, CCNA2, and CCNB1 gene clusters in human breast cancer J Int Med Res. 2021 Apr;49(4):300060520980647._x000D_ 6: Zhou Q, Chen X, He H, Peng S, Zhang Y, Zhang J, Cheng L, Liu S, Huang M, Xie R, Lin T, Huang J. WD repeat domain 5 promotes chemoresistance and Programmed Death-Ligand 1 expression in prostate cancer Theranostics. 2021 Mar 4;11(10):4809-4824._x000D_ 7: Fang Y, Yu H, Liang X, Xu J, Cai X. Chk1-induced CCNB1 overexpression promotes cell proliferation and tumor growth in human colorectal cancer Cancer Biol Ther. 2014 Sep;15(9):1268-79._x000D_ 8: Fang L, Du WW, Awan FM, Dong J, Yang BB. The circular RNA circ-Ccnb1 dissociates Ccnb1/Cdk1 complex suppressing cell invasion and tumorigenesis Cancer Lett. 2019 Sep 10;459:216-226._x000D_ 9: Alfonso-Pérez T, Hayward D, Holder J, Gruneberg U, Barr FA. MAD1-dependent recruitment of CDK1-CCNB1 to kinetochores promotes spindle checkpoint signaling J Cell Biol. 2019 Apr 1;218(4):1108-1117._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/31585531">10: Li B, Cheng J, Wang H, Zhao S, Zhu H, Li C, Zhang Y, Zhao P. CCNB1 affects cavernous sinus invasion in pituitary adenomas through the epithelial-mesenchymal transition J Transl Med. 2019 Oct 4;17(1):336. </a>_x000D_ _x000D_ <strong>Products Related to Human CCNB1 Protein can be found at</strong> <a href="https://moleculardepot.com/product-category/Proteins/"> Proteins</a>