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Rofleponide epimer

Rofleponide epimer is a compound with anti-inflammatory activity. Rofleponide epimer has shown high selectivity in the lungs in experiments. Rofleponide epimer exhibits excellent pharmacological properties by efficiently binding to the rat thymic glucocorticoid receptor. The biotransformation rate of Rofleponide epimer is 10 times higher than that of other known similar drugs, indicating that it has potential application value in inhibiting inflammatory diseases involving mucosa[1].

Product Specifications

CAS Number

144459-71-2

UNSPSC

12352005

Target

Endogenous Metabolite

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/rofleponide-epimer.html

Smiles

OCC([C@]12[C@@]3([C@@]([C@@]4([H])[C@]([C@H](C3)O)([C@@]5(C([C@H](C4)F)=CC(CC5)=O)C)F)([H])C[C@@]1([H])O[C@@H](O2)CCC)C)=O

Molecular Formula

C25H34F2O6

Molecular Weight

468.53

References & Citations

[1]6 alpha-Fluoro- and 6 alpha,9 alpha-difluoro-11 beta,21-dihydroxy-16 alpha,17 alpha-propylmethylenedioxypregn-4-ene-3,20-dione: synthesis and evaluation of activity and kinetics of their C-22 epimers

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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