RORγt inverse agonist 32
RORγt inverse agonist 32 (compound b14) is orally active. RORγt inverse agonist 32 can be used in inflammation research[1].
Product Specifications
CAS Number
[2301159-96-4]
UNSPSC
12352005
Target
ROR
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/rorγt-inverse-agonist-32.html
Smiles
OCC1=CC(S(=O)(N2C(C3=CC=CC=C3C(F)(F)F)CCC2)=O)=CC=C1OCC4CCOCC4
Molecular Formula
C24H28F3NO5S
Molecular Weight
499.54
References & Citations
[1]Qi L, et al. Discovery of novel and potent sulfonamide derivatives as orally available drug for psoriasis. Bioorg Chem. 2024 Oct 5;153:107853.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
RORγ
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