VNI
VNI is an effective inhibitor of CYP51. VNI can inhibit sterol synthesis in Trypanosoma cruzi, exhibiting anti-Trypanosoma cruzi activity[1].
Product Specifications
CAS Number
1246770-52-4
UNSPSC
12352005
Target
Cytochrome P450; Parasite
Type
Reference compound
Related Pathways
Anti-infection; Metabolic Enzyme/Protease
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/vni.html
Smiles
O=C(N[C@H](C1=CC=C(Cl)C=C1Cl)CN2C=CN=C2)C3=CC=C(C4=NN=C(C5=CC=CC=C5)O4)C=C3
Molecular Formula
C26H19Cl2N5O2
Molecular Weight
504.37
References & Citations
[1]Dobish M C, et al. Organocatalytic, enantioselective synthesis of VNI: a robust therapeutic development platform for Chagas, a neglected tropical disease[J]. Organic letters, 2012, 14 (24) : 6322-6325.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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