CdnP-IN-1
CdnP-IN-1 (compound c82) is a potent and selective non-nucleotide MTB CDN PDE (CdnP; Mycobacterium tuberculosis cyclic dinucleotide phosphodiesterase) inhibitor with an IC50 of 18 μM. CdnP-IN-1 does not inhibit the enzymatic activities of three other bacterial CDN PDEs (Yybt, RocR, and GBS-CdnP), a viral CDN PDE (poxin) or mammalian ENPP1[1].
Product Specifications
CAS Number
691862-35-8
UNSPSC
12352005
Target
Phosphodiesterase (PDE)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/cdnp-in-1.html
Smiles
O=C1C2=C(N=CN1CC(NC3=C(OC)C=CC=C3)=O)SC(CC)=C2
Molecular Formula
C17H17N3O3S
Molecular Weight
343.40
References & Citations
Mycobacterium tuberculosis
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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