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Anti-SARS-CoV-2 Spike Antibody, Human IgG1 (9A5E10) (BA.4&BA.5/Omicron Specific) (MALS verified)

It's been reported that SARS-CoV-2 can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.

Product Specifications

Background

It's been reported that SARS-CoV-2 can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.

Host

HEK293

Origin Species

Mouse

Target

Spike protein

Conjugation

Unconjugated

Tag

Human IgG1 | Human Kappa

Stability

● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower. Please avoid repeated freeze-thaw cycles.

Purity

90%

Bioactivity

Immobilized SARS-CoV-2 Spike Trimer, His Tag (BA.5/Omicron) (Cat. No. SPN-C522e) at 1 μg/mL (100 μL/well) can bind Anti-SARS-CoV-2 Spike Antibody, Human IgG1 (9A5E10) (BA.4&BA.5/Omicron Specific) (Cat. No. SPN-M551) with a linear range of 0.2-6 ng/mL (QC tested).

Format

Powder

Buffer

PBS, pH7.4

Additives

Trehalose

Shipping Conditions

RT

Storage Conditions

-20°C

Package Size

500ug*2

Product Datasheet

Https://www.acrobiosystems.com/static/main/products/pdf/ds/SPN-M551.pdf

Species

Mouse

CAS Number

9007-83-4

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