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(R) -GDC-0927

(R) -GDC-0927 ((R) -SRN-927) is a (R) -enantiomer of GDC-0927 (HY-111484) [1].

Product Specifications

CAS Number

[1642297-53-7]

Product Name Alternative

(R) -SRN-927

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Estrogen Receptor/ERR

Type

Reference compound

Related Pathways

Vitamin D Related/Nuclear Receptor

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/r-gdc-0927.html

Concentration

10mM

Purity

98.78

Solubility

DMSO : 50 mg/mL (ultrasonic)

Smiles

OC1=CC=C2C(C(C)=C(C3=CC=CC(O)=C3)[C@@H](C4=CC=C(OCCN5CC(CF)C5)C=C4)O2)=C1

Molecular Formula

C28H28FNO4

Molecular Weight

461.52

Precautions

H302, H315, H319, H335

References & Citations

[1]Wang L, er al. The Quest for Orally Available Selective Estrogen Receptor Degraders (SERDs) . ChemMedChem. 2020 Nov 18;15 (22) :2072-2097.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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