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P110 heptapeptide

Product Specifications

UNSPSC Description

P110 heptapeptide, a peptide inhibitor of Drp1-Fis1 interaction, reduces pathology in numerous models of neurodegeneration, ischemia, and sepsis without blocking the physiological functions of Drp1[1].

Target Antigen

Dynamin

Type

Peptides

Related Pathways

Cytoskeleton

Applications

COVID-19-immunoregulation

Field of Research

Infection; Inflammation/Immunology; Neurological Disease; Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/p110.html

Purity

99.84

Solubility

DMSO : 50 mg/mL (ultrasonic)

Smiles

OC(C[C@H](N)C(N[C@@H](CC(C)C)C(N[C@@H](CC(C)C)C(N1[C@@H](CCC1)C(N[C@@H](CCCNC(N)=N)C(NCC(N[C@@H](CO)C(O)=O)=O)=O)=O)=O)=O)=O)=O

Molecular Weight

756.85

References & Citations

[1]Luis Rios, et al. Targeting an allosteric site in dynamin-related protein 1 to inhibit Fis1-mediated mitochondrial dysfunction. Nat Commun. 2023 Jul 19;14(1):4356.

Shipping Conditions

Blue Ice

Storage Conditions

-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-P10368/P110-heptapeptide-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-P10368/P110-heptapeptide-SDS-MedChemExpress.pdf

Clinical Information

No Development Reported

CAS Number

1411976-18-5

Available Sizes

Curated Selection

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