2,3-Dinor-11beta-prostaglandin F2alpha

2,3-Dinor-11beta-prostaglandin F2alpha (2,3-Dinor-11β-PGF2α) is a metabolite of PGD2. Urinary excretion of 2,3-Dinor-11beta-prostaglandin F2alpha is increased in patients with mast cell activation disease (MCAD) and has been used as a marker of increased PGD2 levels. 2,3-Dinor-11beta-prostaglandin F2alpha levels are also increased in the urine of patients with asthma and are positively correlated with impaired lung function.

Product Specifications

CAS Number

[240405-20-3]

Product Name Alternative

BPG; 2,3-Dinor-11β-PGF2α; 2,3-dinor-11-epi PGF2α

UNSPSC

12352211

Hazard Statement

H225-H319-H350

Target

Prostaglandin Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Endocrinology

Assay Protocol

https://www.medchemexpress.com/2-3-dinor-11beta-prostaglandin-f2alpha.html

Smiles

O=C(O)C/C=C\C[C@@H]1[C@@H](/C=C/[C@@H](O)CCCCC)[C@@H](O)C[C@@H]1O

Molecular Formula

C18H30O5

Molecular Weight

326.43

Precautions

P210-P233-P240-P241-P242-P243-P264-P280-P303+P361+P353-P305+P351+P338-P370+P378-P403+P235-P405-P501

References & Citations

[1]Liston, et al. J. Biol. Chem. 260 (24), 13172-13180 (1985) .

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

Phase 3

Available Sizes

Curated Selection

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