TL8-506
Product Specifications
UNSPSC Description
TL8-506 is a specific TLR8 agonist with an EC50 of 30 nM. TL8-506 can be used for the research of tuberculosis and autoimmune diseases[1].
Target Antigen
Toll-like Receptor (TLR)
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/tl8-506.html
Purity
95.0
Solubility
DMSO : 12.5 mg/mL (ultrasonic)
Smiles
O=C(C1=CC2=CC=C(C3=CC=CC(C#N)=C3)C=C2N=C(N)C1)OCC
Molecular Weight
331.37
References & Citations
[1]Jun Tang, et al. Toll-Like Receptor 8 Agonist Strengthens the Protective Efficacy of ESAT-6 Immunization to Mycobacterium tuberculosis Infection. Front Immunol. 2018 Jan 24;8:1972.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-20457/TL8-506-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-20457/TL8-506-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
1268163-15-0
Available Sizes
Curated Selection
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