Oxypeucedanin (Standard)
Product Specifications
UNSPSC Description
Oxypeucedanin (Standard) is the analytical standard of Oxypeucedanin. This product is intended for research and analytical applications. Oxypeucedanin is a furocoumarin derivative isolated from Angelica dahurica. Oxypeucedanin is a selective open-channel blocker, inhibits the hKv1.5 current with an IC50 value of 76 nM.?Oxypeucedanin prolongs cardiac action potential duration (APD), is a potential antiarrhythmic agent for atrial fibrillation[1]. Oxypeucedanin induces cell?apoptosis through inhibition of cancer cell migration[2].
Target Antigen
Apoptosis; Potassium Channel
Type
Reference Standards
Related Pathways
Apoptosis;Membrane Transporter/Ion Channel
Field of Research
Cancer; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/oxypeucedanin-standard.html
Smiles
CC1(C)C(O1)COC2=C(C=CO3)C3=CC(O4)=C2C=CC4=O
Molecular Weight
286.28
References & Citations
[1]Eun JS, et al. Effects of oxypeucedanin on hKv1.5 and action potential duration.Biol Pharm Bull. 2005 Apr;28(4):657-60.|[2]Yu Liu, et al. Oxypeucedanin hydrate monoacetate isolated from Angelica dahurica induces apoptosis in Caco-2 colon carcinoma cells through the mediation of PI3K-signalling pathway and inhibition of cancer cell migration
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-N0747R/Oxypeucedanin-Standard-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-N0747R/
CAS Number
737-52-0
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