Mannose triflate

Mannose triflate is a glucose analog. Mannose triflate is a precursor for 18F-FDG synthesis for PET applications. Mannose triflate binds to 18F via SN2 nucleophilic substitution reaction. Mannose triflate can be used for an imaging technique in detection of cancer[1][2][3].

Product Specifications

CAS Number

[92051-23-5]

Product Name Alternative

TATM

UNSPSC

12352200

Hazard Statement

H302, H315, H319, H335

Target

Biochemical Assay Reagents

Type

Biochemical Assay Reagents

Related Pathways

Others

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/mannose-triflate.html

Purity

99.79

Solubility

DMSO : ≥ 100 mg/mL

Smiles

CC(O[C@@H]1[C@@H]([C@@H](O[C@@H]([C@H]1OC(C)=O)COC(C)=O)OC(C)=O)OS(C(F)(F)F)(=O)=O)=O

Molecular Formula

C15H19F3O12S

Molecular Weight

480.36

Precautions

H302, H315, H319, H335

References & Citations

[1]Yu S.Review of F-FDG Synthesis and Quality Control. Biomed Imaging Interv J. 2006 Oct;2 (4) :e57|[2]Chirakal R, et al. Base-mediated decomposition of a Mannose triflate during the synthesis of 2-deoxy-2-18F-fluoro-D-glucose[J]. Applied radiation and isotopes, 1995, 46 (3) : 149-155.|[3]Claggett SB, et al. Simplified programming and control of automated radiosynthesizers through unit operations. EJNMMI Res. 2013 Jul 15;3 (1) :53.