IRE1α kinase-IN-10
IRE1α kinase-IN-10 (GP29) is an IRE1α kinase inhibitor. IRE1α kinase-IN-10 can be used for the research of endoplasmic reticulum stress-related diseases[1].
Product Specifications
CAS Number
1415050-59-7
UNSPSC
12352005
Target
IRE1
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ire1α-kinase-in-10.html
Smiles
O=C(NC1=CC=C(C)C(C2=CC3=CN=C(NC4=CC=C(OCCNC(C)=O)C=C4)N=C3C=C2)=C1)C5=CC=CC(C(F)(F)F)=C5
Molecular Formula
C33H28F3N5O3
Molecular Weight
599.60
References & Citations
[1]Wang L, et al. Divergent allosteric control of the IRE1α endoribonuclease using kinase inhibitors. Nat Chem Biol. 2012 Dec;8 (12) :982-9.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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