NNISC-2
Product Specifications
UNSPSC Description
NNISC-2 (compound 4) is a DNA intercalator-linker conjugate of Naph-Se-TMZ (HY-169433), which is composed of DNA intercalator (blue part) Nitro-Naphthalimide-C2-acylamide (HY-169437) and a linker (black part)[1].
Target Antigen
DNA Alkylator/Crosslinker
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Field of Research
cancer
Assay Protocol
https://www.medchemexpress.com/nnisc-2.html
Smiles
O=C1N(CCN=C=[Se])C(C2=C3C(C=C(C=C13)[N+]([O-])=O)=CC=C2)=O
Molecular Weight
374.21
References & Citations
[1]Sharma S, et al. Synthesis and characterization of a novel Naphthalimide-Selenium based Temozolomide drug conjugate in glioma cells. Bioorg Chem. 2024 Nov 26;154:107998.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-169438/NNISC-2-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-169438/
Clinical Information
No Development Reported
CAS Number
2097636-47-8
Curated Selection
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