NNISC-2

NNISC-2 (compound 4) is a DNA intercalator-linker conjugate of Naph-Se-TMZ (HY-169433), which is composed of DNA intercalator (blue part) Nitro-Naphthalimide-C2-acylamide (HY-169437) and a linker (black part) [1].

Product Specifications

CAS Number

[2097636-47-8]

UNSPSC

12352005

Target

DNA Alkylator/Crosslinker

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/nnisc-2.html

Smiles

O=C1N(CCN=C=[Se])C(C2=C3C(C=C(C=C13)[N+]([O-])=O)=CC=C2)=O

Molecular Formula

C15H9N3O4Se

Molecular Weight

374.21

References & Citations

[1]Sharma S, et al. Synthesis and characterization of a novel Naphthalimide-Selenium based Temozolomide drug conjugate in glioma cells. Bioorg Chem. 2024 Nov 26;154:107998.