KRAS ligand 5
KRAS ligand 5 is the target protein ligand for PROTAC K-Ras Degrader-3 (HY-168054) . PROTAC K-Ras Degrader-3 can specifically degrade KRAS mutated proteins[1].
Product Specifications
CAS Number
[3043896-37-0]
UNSPSC
12352005
Target
Ligands for Target Protein for PROTAC; Ras
Type
Reference compound
Related Pathways
GPCR/G Protein; MAPK/ERK Pathway; PROTAC
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/kras-ligand-5.html
Smiles
FC1=C(CC)C2=C(C3=C(F)C4=NC(OCC5(C=O)CC5)=NC(N6C[C@@](O)(C)CCC6)=C4C=N3)C=C(O)C=C2C=C1
Molecular Formula
C30H30F2N4O4
Molecular Weight
548.58
References & Citations
[1]LUO, Robert, et al. Glutarimide-containing pan-kras-mutant degrader compounds and uses thereof. WO2024118966. 2024 June 6.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
GTR15191604 1 Vial
Lentiviral mouse Zbtb42 shRNA (UAS) - Lentiviral mouse Zbtb42 shRNA (UAS, RFP) (100)
Ask
View Details RC201249L4V 200 µL
Histone H1.2 (HIST1H1C) (NM_005319) Human Tagged ORF Clone Lentiviral Particle
Ask
View Details