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KRAS ligand 5

KRAS ligand 5 is the target protein ligand for PROTAC K-Ras Degrader-3 (HY-168054) . PROTAC K-Ras Degrader-3 can specifically degrade KRAS mutated proteins[1].

Product Specifications

CAS Number

[3043896-37-0]

UNSPSC

12352005

Target

Ligands for Target Protein for PROTAC; Ras

Type

Reference compound

Related Pathways

GPCR/G Protein; MAPK/ERK Pathway; PROTAC

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/kras-ligand-5.html

Smiles

FC1=C(CC)C2=C(C3=C(F)C4=NC(OCC5(C=O)CC5)=NC(N6C[C@@](O)(C)CCC6)=C4C=N3)C=C(O)C=C2C=C1

Molecular Formula

C30H30F2N4O4

Molecular Weight

548.58

References & Citations

[1]LUO, Robert, et al. Glutarimide-containing pan-kras-mutant degrader compounds and uses thereof. WO2024118966. 2024 June 6.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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