KRAS ligand 5
KRAS ligand 5 is the target protein ligand for PROTAC K-Ras Degrader-3 (HY-168054) . PROTAC K-Ras Degrader-3 can specifically degrade KRAS mutated proteins[1].
Product Specifications
CAS Number
[3043896-37-0]
UNSPSC
12352005
Target
Ligands for Target Protein for PROTAC; Ras
Type
Reference compound
Related Pathways
GPCR/G Protein; MAPK/ERK Pathway; PROTAC
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/kras-ligand-5.html
Smiles
FC1=C(CC)C2=C(C3=C(F)C4=NC(OCC5(C=O)CC5)=NC(N6C[C@@](O)(C)CCC6)=C4C=N3)C=C(O)C=C2C=C1
Molecular Formula
C30H30F2N4O4
Molecular Weight
548.58
References & Citations
[1]LUO, Robert, et al. Glutarimide-containing pan-kras-mutant degrader compounds and uses thereof. WO2024118966. 2024 June 6.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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