Minaprine (dihydrochloride)

Minaprine dihydrochloride is a reversible inhibitor of MAO-A; weakly inhibit acetylcholinesterase; an antidepressant for treatment of depression.

Product Specifications

CAS Number

[25953-17-7]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Monoamine Oxidase

Type

Reference compound

Related Pathways

Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/Minaprine-dihydrochloride.html

Concentration

10mM

Purity

99.90

Solubility

DMSO : ≥ 100 mg/mL|H2O : 100 mg/mL (ultrasonic)

Smiles

[H]Cl.CC1=CC(C2=CC=CC=C2)=NN=C1NCCN3CCOCC3.[H]Cl

Molecular Formula

C17H24Cl2N4O

Molecular Weight

371.30

Precautions

H302, H315, H319, H335

References & Citations

[1]Kan JP, et al. Effect of the antidepressant minaprine on both forms of monoamine oxidase in the rat. Biochem Pharmacol. 1986 Mar 15;35 (6) :973-8.|[2]Contreras JM, et al. Aminopyridazines as acetylcholinesterase inhibitors. J Med Chem. 1999 Feb 25;42 (4) :730-41.