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C16 1-Deoxyceramide (m18:1/16:0)

C16 1-Deoxyceramide (m18:1/16:0) (C16:0 1-Deoxyceramide) is a lipid molecule, which is composed of a long-chain fatty acid (16:0) and a 1-deoxysphingoid backbone. Deoxyceramide accumulates under the conditions of obesity and type 2 diabetes (T2D) . Deoxyceramide is unable to be further metabolized to more complex sphingolipid, and is toxic when accumulates in the body. Deoxyceramide increases in differentiated adipocytes in vitro[1].

Product Specifications

CAS Number

1246298-56-5

Product Name Alternative

C16:0 1-Deoxyceramide; C16:0 Ceramide (m18:1/16:0) ; Cer (m18:1/16:0)

UNSPSC

12352211

Target

Endogenous Metabolite

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/c16-1-deoxyceramide-m18-1-16-0.html

Smiles

CCCCCCCCCCCCC/C=C/[C@@H](O)[C@H](C)NC(CCCCCCCCCCCCCCC)=O

Molecular Formula

C34H67NO2

Molecular Weight

521.90

References & Citations

[1]Hannich JT, et al., Ether lipids, sphingolipids and toxic 1-deoxyceramides as hallmarks for lean and obese type 2 diabetic patients. Acta Physiol (Oxf) . 2021 May;232 (1) :e13610.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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