6-Maleimidocaproic acid sulfo-NHS (sodium)
6-Maleimidocaproic acid sulfo-NHS (Sulfo-EMCS) sodium is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Product Specifications
CAS Number
[215312-86-0]
Product Name Alternative
Sulfo-EMCS
UNSPSC
12352200
Hazard Statement
H315, H319
Target
PROTAC Linkers
Type
Biochemical Assay Reagents
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/6-maleimidocaproic-acid-sulfo-nhs-sodium.html
Purity
98.91
Smiles
O=C(ON1C(C(S(=O)(O[Na])=O)CC1=O)=O)CCCCCN2C(C=CC2=O)=O
Molecular Formula
C14H15N2NaO9S
Molecular Weight
410.33
Precautions
H315, H319
References & Citations
[1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Biochemical Assay Reagents
Clinical Information
No Development Reported
Available Sizes
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