Milacemide
Milacemide, a glycinamide derivative, is an orally active MAO-B inhibitor with anticonvulsant activity. Milacemide reduces the levels of dihydroxyphenylacetic acid and homovanilic acid, but increases the levels of dopamine and serotonin in the caudate nucleus. Milacemide is promising for research of Alzheimer's disease[1][2].
Product Specifications
CAS Number
[76990-56-2]
UNSPSC
12352211
Hazard Statement
H315, H319, H335
Target
Monoamine Oxidase
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/milacemide.html
Purity
98.04
Smiles
O=C(CNCCCCC)N
Molecular Formula
C7H16N2O
Molecular Weight
144.21
Precautions
H315, H319, H335
References & Citations
[1]Khandwala H, et al. Milacemide, a glycine pro-drug, inhibits strychnine-allodynia without affecting normal nociception in the rat. Pain. 1998 Jul;77 (1) :87-95.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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