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PI3Kα-IN-24

PI3Kα-IN-24 (WR23) is a PI3Kα inhibitor with an IC50 of 0.025 μM and exhibits a significant pAktSer473 suppression effect. PI3Kα-IN-24 can be utilized in cancer research[1].

Product Specifications

CAS Number

1350960-66-5

UNSPSC

12352005

Target

PI3K

Type

Reference compound

Related Pathways

PI3K/Akt/mTOR

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/pi3kα-in-24.html

Smiles

O=S(C1=CC=C(C=C1)Br)(C2=NC3=C(N=C2N4CCC(CC4)O)C=CC=C3)=O

Molecular Formula

C19H18BrN3O3S

Molecular Weight

448.33

References & Citations

[1]Wu P, et al. Discovery of novel 2-piperidinol-3- (arylsulfonyl) quinoxalines as phosphoinositide 3-kinase α (PI3Kα) inhibitors. Bioorg Med Chem. 2012 May 1;20 (9) :2837-44.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

PI3Kα

Frequently Asked Questions

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