PI3Kα-IN-24
PI3Kα-IN-24 (WR23) is a PI3Kα inhibitor with an IC50 of 0.025 μM and exhibits a significant pAktSer473 suppression effect. PI3Kα-IN-24 can be utilized in cancer research[1].
Product Specifications
UNSPSC
12352005
Target
PI3K
Type
Reference compound
Related Pathways
PI3K/Akt/mTOR
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/pi3kα-in-24.html
Smiles
O=S(C1=CC=C(C=C1)Br)(C2=NC3=C(N=C2N4CCC(CC4)O)C=CC=C3)=O
Molecular Formula
C19H18BrN3O3S
Molecular Weight
448.33
References & Citations
[1]Wu P, et al. Discovery of novel 2-piperidinol-3- (arylsulfonyl) quinoxalines as phosphoinositide 3-kinase α (PI3Kα) inhibitors. Bioorg Med Chem. 2012 May 1;20 (9) :2837-44.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-116563/PI3Kα-IN-24-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-116563/
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PI3Kα
CAS Number
[1350960-66-5]
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