Tavaborole

Tavaborole (AN-2690) is an antifungal agent with activity against Trichophyton species, in a topical solution formulation for the potential treatment of onychomycosis.

Product Specifications

CAS Number

[174671-46-6]

Product Name Alternative

AN-2690

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Antibiotic; Fungal

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/AN-2690.html

Purity

99.74

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

OB1OCC2=CC(F)=CC=C21

Molecular Formula

C7H6BFO2

Molecular Weight

151.93

Precautions

H302, H315, H319, H335

References & Citations

[1]Baker SJ, et al. Discovery of a new boron-containing antifungal agent, 5-fluoro-1,3-dihydro-1-hydroxy-2,1- benzoxaborole (AN2690), for the potential treatment of onychomycosis. J Med Chem. 2006 Jul 27;49 (15) :4447-50.|[2]Zhou XL, et al. Post-transfer editing by a eukaryotic leucyl-tRNA synthetase resistant to the broad-spectrum drug AN2690. Biochem J. 2010 Sep 1;430 (2) :325-33.