Isovalerylcarnitine-d9-1 (chloride)
Isovalerylcarnitine-d9-1 (chloride) is deuterium labeled Isovalerylcarnitine (chloride) . Isovalerylcarnitine chloride, a product of the catabolism of L-leucine, is a potent activator of the Ca2+-dependent proteinase (calpain) of human neutrophils[1][2].
Product Specifications
UNSPSC
12352211
Target
Endogenous Metabolite; Isotope-Labeled Compounds; Proteasome
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease; Others
Field of Research
Metabolic Disease
Smiles
O=C(O[C@H](CC(O)=O)C[N+](C)(C)C)C([2H])(C(C([2H])([2H])[2H])(C([2H])([2H])[2H])[2H])[2H].[Cl-]
Molecular Formula
C12H15D9ClNO4
Molecular Weight
290.83
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.|[2]Pontremoli S, et al. Isovalerylcarnitine is a specific activator of calpain of human neutrophils. Biochem Biophys Res Commun. 1987 Nov 13;148 (3) :1189-95.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Frequently Asked Questions
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