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PIP-C-3-Azaspiro[5.5]undecane-boc

PIP-C-3-Azaspiro[5.5]undecane-boc is the linker for PROTAC. PIP-C-3-Azaspiro[5.5]undecane-boc is utilized for synthesis of PROTAC SOS1 degrader-10.

Product Specifications

CAS Number

3027978-51-1

UNSPSC

12352005

Target

PROTAC Linkers

Type

Reference compound

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/pip-c-3-azaspiro-5-5-undecane-boc.html

Solubility

10 mM in DMSO

Smiles

O=C(OC(C)(C)C)N1CCC(CC2)(CC1)CCC2CN3CCNCC3

Molecular Formula

C20H37N3O2

Molecular Weight

351.53

References & Citations

[1]Wang, K, et al. “Design, synthesis, and bioevaluation of SOS1 PROTACs derived from pyrido[2,3-d]pyrimidin-7-one-based SOS1 inhibitor.” Bioorganic & medicinal chemistry letters vol. 107 (2024) : 129780.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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