PIP-C-3-Azaspiro[5.5]undecane-boc
PIP-C-3-Azaspiro[5.5]undecane-boc is the linker for PROTAC. PIP-C-3-Azaspiro[5.5]undecane-boc is utilized for synthesis of PROTAC SOS1 degrader-10.
Product Specifications
CAS Number
3027978-51-1
UNSPSC
12352005
Target
PROTAC Linkers
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/pip-c-3-azaspiro-5-5-undecane-boc.html
Solubility
10 mM in DMSO
Smiles
O=C(OC(C)(C)C)N1CCC(CC2)(CC1)CCC2CN3CCNCC3
Molecular Formula
C20H37N3O2
Molecular Weight
351.53
References & Citations
[1]Wang, K, et al. “Design, synthesis, and bioevaluation of SOS1 PROTACs derived from pyrido[2,3-d]pyrimidin-7-one-based SOS1 inhibitor.” Bioorganic & medicinal chemistry letters vol. 107 (2024) : 129780.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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