ST3 β-Gal α-2,3-Sialyltransferase 5
ST3 β-Gal α-2,3-Sialyltransferase 5 (ST3GAL5) is a glycosphingolipid (GSL) biosynthetic enzyme that can inhibit TGF-β-induced epithelial-mesenchymal transition (EMT), invasion, and metastasis both in vivo and in vitro. ST3 β-Gal α-2,3-Sialyltransferase 5 can be used in cancer research[1].
Product Specifications
Product Name Alternative
ST3GAL5
UNSPSC
12352204
Target
TGF-beta/Smad
Type
Enzyme
Related Pathways
Stem Cell/Wnt; TGF-beta/Smad
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/st3-β-gal-α-2-3-sialyltransferase-5.html
Solubility
10 mM in DMSO
Smiles
[ST3b-Gala-2,3-Sialyltransferase5]
References & Citations
[1]Zhang J, et al. ST3GAL5-catalyzed gangliosides inhibit TGF-β-induced epithelial-mesenchymal transition via TβRI degradation. EMBO J. 2023 Jan 16;42 (2) :e110553.
Shipping Conditions
Room temperature
Scientific Category
Enzyme
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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