4-IPP
4-IPP (4-Iodo-6-phenylpyrimidine) is a specific suicide substrate and irreversible inhibitor of macrophage migration inhibitory factor (MIF) [1].
Product Specifications
CAS Number
41270-96-6
Product Name Alternative
4-Iodo-6-phenylpyrimidine
UNSPSC
12352005
Hazard Statement
H302, H315, H318, H335
Target
Macrophage migration inhibitory factor (MIF)
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/4-ipp.html
Purity
99.46
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
IC1=CC(C2=CC=CC=C2)=NC=N1
Molecular Formula
C10H7IN2
Molecular Weight
282.08
Precautions
H302, H315, H318, H335
References & Citations
[1]Zheng L, et al. Macrophage migration inhibitory factor (MIF) inhibitor 4-IPP suppresses osteoclast formation and promotes osteoblast differentiation through the inhibition of the NF-κB signaling pathway. FASEB J. 2019 Jun;33 (6) :7667-7683.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
13730061 1.0 µg DNA
C11orf92 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)
Sign In for Pricing
View Details MBS6359340-01 0.1 mL
TSC2, Phosphorylated (S1365) (Tsc2, Tuberin, Tuberous sclerosis 2 protein homolog) (MaxLight 750)
Sign In for Pricing
View Details MBS6359340-02 5x 0.1 mL
TSC2, Phosphorylated (S1365) (Tsc2, Tuberin, Tuberous sclerosis 2 protein homolog) (MaxLight 750)
Sign In for Pricing
View Details