4-IPP
Product Specifications
UNSPSC Description
4-IPP (4-Iodo-6-phenylpyrimidine) is a specific suicide substrate and irreversible inhibitor of macrophage migration inhibitory factor (MIF)[1].
Target Antigen
Macrophage migration inhibitory factor (MIF)
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/4-ipp.html
Purity
99.46
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
IC1=CC(C2=CC=CC=C2)=NC=N1
Molecular Weight
282.08
References & Citations
[1]Zheng L, et al. Macrophage migration inhibitory factor (MIF) inhibitor 4-IPP suppresses osteoclast formation and promotes osteoblast differentiation through the inhibition of the NF-κB signaling pathway. FASEB J. 2019 Jun;33(6):7667-7683.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-110063/4-IPP-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-110063/4-IPP-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
41270-96-6
Available Sizes
Curated Selection
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