PreQ1-biotin
PreQ1-biotin is a biotin conjugated preQ1 substrate. PreQ1-biotin is used for RNA-TAG (transglycosylation at guanosine) and DNA-TAG. PreQ1-biotin can be used for affinity tagging and pull-down of specific RNAs that have been modified selectively by E. coli tRNA guanine transglycosylase (TGT) [1].
Product Specifications
CAS Number
[2971850-25-4]
UNSPSC
12352005
Target
Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/preq1-biotin.html
Smiles
O=C1N=C(NC2=C1C(CNCCCCCCNC(CCCCC3SCC4NC(NC34)=O)=O)=CN2)N
Molecular Formula
C23H36N8O3S
Molecular Weight
504.65
References & Citations
[1]Tota EM, Devaraj NK. Site-specific Covalent Labeling of DNA Substrates by an RNA Transglycosylase. bioRxiv [Preprint]. 2023 Jan 23:2023.01.23.525207.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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