PreQ1-biotin

PreQ1-biotin is a biotin conjugated preQ1 substrate. PreQ1-biotin is used for RNA-TAG (transglycosylation at guanosine) and DNA-TAG. PreQ1-biotin can be used for affinity tagging and pull-down of specific RNAs that have been modified selectively by E. coli tRNA guanine transglycosylase (TGT) [1].

Product Specifications

CAS Number

[2971850-25-4]

UNSPSC

12352005

Target

Bacterial

Type

Reference compound

Related Pathways

Anti-infection

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/preq1-biotin.html

Smiles

O=C1N=C(NC2=C1C(CNCCCCCCNC(CCCCC3SCC4NC(NC34)=O)=O)=CN2)N

Molecular Formula

C23H36N8O3S

Molecular Weight

504.65

References & Citations

[1]Tota EM, Devaraj NK. Site-specific Covalent Labeling of DNA Substrates by an RNA Transglycosylase. bioRxiv [Preprint]. 2023 Jan 23:2023.01.23.525207.