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Anti-Hu CD344 PE

CD344 (Frizzled class receptor 4) is a G-protein coupled 7-TM protein, predominantly expressed in fetal neuronal progenitor cells, neuronal intestinal cells, as well as in the kidney, lung, brain, and liver. CD344 is important for regulation of cell polarity, proliferation, and tissue development. Defects in CD344 expression, or its mutation, lead e.g. to serious failures in retinal vascularization, defects in cerebellum, progressive hearing loss, or impaired corpora lutea formation and function.

Product Specifications

Certification

RUO

Reactivity

Human, Non-human primates

Immunogen

WERI-RB-1 retinoblastoma cells

Target Antigen

CD344

Clone

CH3A4A7

Applications

FC (QC tested)

Format

PE

Buffer

Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

References & Citations

*Nothelfer K, Obermayr F, Belz N, Reinartz E, Bareiss PM, Bühring HJ, Beschorner R, Just L: Expression of the Wnt Receptor Frizzled-4 in the Human Enteric Nervous System of Infants. Stem Cells Int. 2016;2016:9076823., URL: https://www.ncbi.nlm.nih.gov/pubmed/26697080

Storage Conditions

Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.

Specificity

The mouse monoclonal antibody CH3A4A7 recognizes an extracellular epitope of CD344 (Frizzled 4), a 7-TM protein of G-protein-coupled receptor family, which is a marker for neuronal stem cells.

Applications Notes

6

Isotype

Mouse IgG1 kappa

Frequently Asked Questions

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