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Pregnenolone (Standard)

Pregnenolone (Standard) is the analytical standard of Pregnenolone. This product is intended for research and analytical applications. Pregnenolone (3β-Hydroxy-5-pregnen-20-one) is a powerful neurosteroid, the main precursor of various steroid hormones including steroid ketones. Pregnenolone acts as a signaling-specific inhibitor of cannabinoid CB1 receptor, inhibits the effects of tetrahydrocannabinol (THC) that are mediated by the CB1 receptors. Pregnenolone can protect the brain from cannabis intoxication[1][2]. Pregnenolone is also a TRPM3 channel activator, and also can weakly activate TRPM1 channels[3].

Product Specifications

CAS Number

[145-13-1]

Product Name Alternative

3β-Hydroxy-5-pregnen-20-one (Standard)

UNSPSC

12352211

Hazard Statement

H302-H312-H332-H361

Target

Autophagy; Cannabinoid Receptor; Endogenous Metabolite; Reference Standards; TRP Channel

Type

Reference Standards

Related Pathways

Autophagy; GPCR/G Protein; Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease; Neuronal Signaling; Others

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/pregnenolone-standard.html

Purity

99.91

Smiles

C[C@@](C1=CC2)(CC[C@H](O)C1)[C@]3([H])[C@]2([H])[C@@](CC[C@@H]4C(C)=O)([H])[C@]4(C)CC3

Molecular Formula

C21H32O2

Molecular Weight

316.48

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P363-P405-P501

Shipping Conditions

Room Temperature

Storage Conditions

4°C, sealed storage, away from light and moisture

Scientific Category

Reference Standards

Clinical Information

Phase 4

Isoform

CB1; Human Endogenous Metabolite

Available Sizes

Curated Selection

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