Pregnenolone (Standard)
Pregnenolone (Standard) is the analytical standard of Pregnenolone. This product is intended for research and analytical applications. Pregnenolone (3β-Hydroxy-5-pregnen-20-one) is a powerful neurosteroid, the main precursor of various steroid hormones including steroid ketones. Pregnenolone acts as a signaling-specific inhibitor of cannabinoid CB1 receptor, inhibits the effects of tetrahydrocannabinol (THC) that are mediated by the CB1 receptors. Pregnenolone can protect the brain from cannabis intoxication[1][2]. Pregnenolone is also a TRPM3 channel activator, and also can weakly activate TRPM1 channels[3].
Product Specifications
CAS Number
[145-13-1]
Product Name Alternative
3β-Hydroxy-5-pregnen-20-one (Standard)
UNSPSC
12352211
Hazard Statement
H302-H312-H332-H361
Target
Autophagy; Cannabinoid Receptor; Endogenous Metabolite; Reference Standards; TRP Channel
Type
Reference Standards
Related Pathways
Autophagy; GPCR/G Protein; Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease; Neuronal Signaling; Others
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/pregnenolone-standard.html
Purity
99.91
Smiles
C[C@@](C1=CC2)(CC[C@H](O)C1)[C@]3([H])[C@]2([H])[C@@](CC[C@@H]4C(C)=O)([H])[C@]4(C)CC3
Molecular Formula
C21H32O2
Molecular Weight
316.48
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P363-P405-P501
Shipping Conditions
Room Temperature
Storage Conditions
4°C, sealed storage, away from light and moisture
Scientific Category
Reference Standards
Clinical Information
Phase 4
Isoform
CB1; Human Endogenous Metabolite
Available Sizes
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