7-Iodo-7-deaza-2'-deoxyguanosine

7-Iodo-7-deaza-2'-deoxyguanosine (7-Deaza-7-Iodo-2'-deoxyguanosine) is a deoxyguanosine derivative that can be used in DNA synthesis and sequencing reactions. 7-Iodo-7-deaza-2'-deoxyguanosine can be prepared analogously by triphosphorylation of the corresponding nucleoside[1][2].

Product Specifications

CAS Number

[172163-62-1]

Product Name Alternative

7-Deaza-7-Iodo-2'-deoxyguanosine

UNSPSC

12352200

Hazard Statement

H302, H315, H319, H335

Target

DNA/RNA Synthesis

Type

Biochemical Assay Reagents

Related Pathways

Cell Cycle/DNA Damage

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/7-iodo-7-deaza-2-deoxyguanosine.html

Purity

99.84

Solubility

DMSO : 125 mg/mL (ultrasonic)

Smiles

OC[C@H]1O[C@@H](N2C(N=C(N)NC3=O)=C3C(I)=C2)C[C@@H]1O

Molecular Formula

C11H13IN4O4

Molecular Weight

392.15

Precautions

H302, H315, H319, H335

References & Citations

[1]Ronald Graham, et al. Nucleotide cleavable linkers and uses thereof. WO2020146397A1.|[2]Sýkorová, V., et al., (2022) . Polymerase Synthesis of DNA Containing Iodinated Pyrimidine or 7-Deazapurine Nucleobases and Their Post-synthetic Modifications through the Suzuki-Miyaura Cross-Coupling Reactions. Chembiochem : a European journal of chemical biology, 23 (3), e202100608.