BmrA (B. subtilis 168)

<strong>BmrA (B. subtilis 168)</strong>_x000D_ <strong>Catalog number:</strong> B2017316_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 10 µg_x000D_ <strong>Molecular Weight or Concentration:</strong> 64.5 kDa_x000D_ <strong>Supplied as:</strong> Solution_x000D_ <strong>Applications:</strong> a molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> −80°C_x000D_ <strong>Keywords:</strong> Multidrug Resistance ABC Transporter ATP-binding/permease Protein BmrA_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Oepen K, Mater V, Schneider D. Unfolding Individual Domains of BmrA, a Bacterial ABC Transporter Involved in Multidrug Resistance Int J Mol Sci. 2023 Mar 9;24(6):5239._x000D_ 2: Gobet A, Jaxel C, Magnard S, Garrigos M, Orlowski S, Jamin N, Falson P, Chaptal V. Overexpression of the ABC Transporter BmrA Within Intracellular Caveolae in Escherichia coli Methods Mol Biol. 2022;2507:79-89._x000D_ 3: Serçinoğlu O, Senturk D, Altinisik Kaya FE, Avci FG, Frlan R, Tomašič T, Ozbek P, Orelle C, Jault JM, Sariyar Akbulut B. Identification of novel inhibitors of the ABC transporter BmrA Bioorg Chem. 2020 Dec;105:104452._x000D_ 4: Lacabanne D, Wiegand T, Di Cesare M, Orelle C, Ernst M, Jault JM, Meier BH, Böckmann A. Solid-State NMR Reveals Asymmetric ATP Hydrolysis in the Multidrug ABC Transporter BmrA J Am Chem Soc. 2022 Jul 13;144(27):12431-12442._x000D_ 5: Oepen K, Özbek H, Schüffler A, Liermann JC, Thines E, Schneider D. Myristic Acid Inhibits the Activity of the Bacterial ABC Transporter BmrA Int J Mol Sci. 2021 Dec 17;22(24):13565._x000D_ 6: Pérez Carrillo VH, Rose-Sperling D, Tran MA, Wiedemann C, Hellmich UA. Backbone NMR assignment of the nucleotide binding domain of the Bacillus subtilis ABC multidrug transporter BmrA in the post-hydrolysis state Biomol NMR Assign. 2022 Apr;16(1):81-86._x000D_ 7: Ravaud S, Do Cao MA, Jidenko M, Ebel C, Le Maire M, Jault JM, Di Pietro A, Haser R, Aghajari N. The ABC transporter BmrA from Bacillus subtilis is a functional dimer when in a detergent-solubilized state Biochem J. 2006 Apr 15;395(2):345-53._x000D_ 8: Lacabanne D, Orelle C, Lecoq L, Kunert B, Chuilon C, Wiegand T, Ravaud S, Jault JM, Meier BH, Böckmann A. Flexible-to-rigid transition is central for substrate transport in the ABC transporter BmrA from Bacillus subtilis Commun Biol. 2019 Apr 29;2:149._x000D_ 9: Wiseman B, Kilburg A, Chaptal V, Reyes-Mejia GC, Sarwan J, Falson P, Jault JM. Stubborn contaminants: influence of detergents on the purity of the multidrug ABC transporter BmrA PLoS One. 2014 Dec 17;9(12):e114864._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/24630999">10: Fribourg PF, Chami M, Sorzano CO, Gubellini F, Marabini R, Marco S, Jault JM, Lévy D. 3D cryo-electron reconstruction of BmrA, a bacterial multidrug ABC transporter in an inward-facing conformation and in a lipidic environment J Mol Biol. 2014 May 15;426(10):2059-69. </a>_x000D_ _x000D_ <strong>Products Related to BmrA (B. subtilis 168) can be found at</strong> <a href="https://moleculardepot.com/product-category/Proteins/"> Proteins</a>