KRP-101

KRP-101 is a compound that regulates the expression of genes related to lipid metabolism. It is a PPARα agonist that can highly sensitively regulate the expression of genes such as apolipoprotein A-IV, which may be related to lowering serum triglycerides and increasing HDL.

Product Specifications

CAS Number

[311770-26-0]

UNSPSC

12352005

Target

PPAR

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage; Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/krp-101.html

Smiles

FC(C=C1)=CC=C1OC(C=C2)=CC=C2CNC(C3=C(C=CC(C[C@H](CC)C(O)=O)=C3)OC)=O

Molecular Formula

C26H26FNO5

Molecular Weight

451.49

References & Citations

[1]Highly sensitive upregulation of apolipoprotein A-IV by peroxisome proliferator-activated receptor alpha (PPARalpha) agonist in human hepatoma cells