AM 92016
AM 92016 is a potassium channel blocker. AM 92016 can increase the duration of action potentials in isolated ventricular cells from guinea pigs and rabbits. AM 92016 has proarrhythmic activity in guinea pigs and pigs[1].
Product Specifications
CAS Number
178894-81-0
UNSPSC
12352005
Target
Potassium Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/am-92016.html
Smiles
O=C(C1=CC=CC=C1)O.O=S(NC2=CC=C(C=C2)OCC(CN(CCC3=CC=C(C(Cl)=C3)Cl)C)O)(C)=O
Molecular Formula
C26H30Cl2N2O6S
Molecular Weight
569.50
References & Citations
[1]Hagerty MJ, et al. The in-vivo cardiovascular effects of a putative class III anti-arrhythmic drug, AM 92016. J Pharm Pharmacol. 1996 Apr;48 (4) :417-21.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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