BMT-297376
BMT-297376, the optimized Linrodostat, is a potent IDO1 inhibitor[1].
Product Specifications
CAS Number
2251031-81-7
UNSPSC
12352005
Target
Indoleamine 2,3-Dioxygenase (IDO)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/bmt-297376.html
Purity
99.14
Solubility
DMSO : 100 mg/mL (ultrasonic) |Methanol : ≥ 100 mg/mL
Smiles
FC(C1=C(OC)N=CC=C1[C@H]2CC[C@@](CC2)([H])[C@@H](CC)NC(C3=CN=C(OC)C=C3)=O)F
Molecular Formula
C23H29F2N3O3
Molecular Weight
433.49
References & Citations
[1]Roshan Y. Nimje, et al. Development of a Stereoselective and Scalable Synthesis for the Potent Indoleamine 2,3-Dioxygenase 1 (IDO1) Inhibitor, BMT-297376; N- ((R) -1- ((cis) -4- (3- (Difluoromethyl) -2-methoxypyridin-4-yl) cyclohexyl) propyl) -6-methoxynicotinamide. Org. Process Res. Dev. 2021, 25, 7, 1680-1689.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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