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Isopteropodine (Standard)

Isopteropodine (Standard) is the analytical standard of Isopteropodine (HY-N4157) . This product is intended for research and analytical applications. Isopteropodine is a positive modulator that selectively acts on muscarinic M1 and 5-HT2 receptors. Isopteropodine has an EC50 of 9.92 μM for acetylcholine and 14.5 μM for 5-HT. Isopteropodine also has antibacterial activity against Gram-positive bacteria, with MICs of 150 μg/mL and 250 μg/mL for Staphylococcus aureus and Bacillus subtilis, respectively. Isopteropodine enhances receptor function by increasing the affinity of agonists for receptors and can also inhibit the growth of specific Gram-positive bacteria, and can be used in cognitive impairment and antibacterial research[1][2].

Product Specifications

CAS Number

[5171-37-9]

UNSPSC

12352005

Target

5-HT Receptor; Bacterial; mAChR; Reference Standards

Type

Reference Standards

Related Pathways

Anti-infection; GPCR/G Protein; Neuronal Signaling; Others

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/isopteropodine-standard.html

Smiles

O=C(C1=CO[C@@H](C)[C@]([C@]1([H])C[C@]23[H])([H])CN2CC[C@]43C(NC5=C4C=CC=C5)=O)OC

Molecular Formula

C21H24N2O4

Molecular Weight

368.43

References & Citations

[1]Kang TH, et al. Pteropodine and isopteropodine positively modulate the function of rat muscarinic M (1) and 5-HT (2) receptors expressed in Xenopus oocyte. Eur J Pharmacol. 2002 May 24;444 (1-2) :39-45.|[2]García R, et al. Antimicrobial activity of isopteropodine. Z Naturforsch C J Biosci. 2005 May-Jun;60 (5-6) :385-8.

Shipping Conditions

Room temperature

Scientific Category

Reference Standards

Isoform

5-HT2 Receptor; mAChR1

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